Michael Polansky’s Outer Bio launched with $23M and an unusual pitch: not a drug company, but an AI platform screening compounds on living human skin.
Sequencing eight Myotis bat species uncovered genetic tricks linking their famous virus tolerance to cancer resistance and longevity — clues that could inform human aging research.
Priovant’s brepocitinib is the first pill approved for the rare autoimmune disease — in a trial, more patients improved and got off steroids than on placebo.
Using Britain’s postwar sugar rationing as a natural experiment, researchers found that lower early-life sugar exposure tracked with less cancer and slower biological aging decades on — though it can’t prove cause.
The TSLP-blocking antibody met its goals in a Phase 3 eosinophilic esophagitis trial, setting up a potential third indication and a challenge to Sanofi’s Dupixent.
Zipalertinib plus chemo so clearly slowed a hard-to-treat form of lung cancer that the trial was stopped early — setting up a fight with drugs from J&J and AstraZeneca.
By deliberately removing the antibody response that can backfire against dengue, researchers built an experimental Zika vaccine that defended mice using T cells instead.
The partnership will use quantum algorithms to design better photosensitizers — molecules that kill tumor cells when hit with light — a task classical computers struggle with.
In 340,000 UK adults, low-to-moderate wine drinking was tied to lower heart-death risk while beer and spirits were tied to higher — but it’s observational, not proof.
Studying 107 adults aged 26 to 86, researchers found that aging muscles increasingly tense against each other around the ankle — a “safety-first” stiffening that saps push-off power.
The renewed alliance keeps subspecialty expertise, tumor conferences and clinical-trial access available to patients closer to home, with new local cancer services coming this autumn.
The Raleigh biotech priced its Nasdaq debut at $13 a share to fund mizagliflozin, an oral drug aimed at the dangerous blood-sugar crashes some patients face after bariatric surgery.